What is the mechanism of action of this medication? What will it accomplish for me?
Clobetasol is a topical (skin-applied) corticosteroid medicine used to treat skin disorders such as moderate to severe psoriasis and eczematous dermatitis that have not reacted well to other corticosteroids. Scalp lotion and shampoo are used to treat scalp psoriasis and seborrheic dermatitis. Clobetasol relieves edoema, redness, and itching.
This drug may be offered under several brand names and/or in several forms;
Your doctor may have prescribed this medication for a condition not specified in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medicine, speak to your doctor. Do not discontinue this medicine without first visiting your doctor.
Even if they have the same symptoms as you, do not give this drug to anybody else. If a person does not have a prescription for this dermovate cream , it can be dangerous.
This drug is available in what form(s)?
Cream 0.05%
Clobetasol 17-propionate is 0.5 milligrammes per gramme. Cetyl alcohol, chlorocresol, citric acid, glyceryl monostearate, glyceryl stearate/PEG 100 stearate, propylene glycol, purified water, stearyl alcohol, sodium citrate, and white wax are nonmedicinal components.
0.5% ointment;
Clobetasol 17-propionate is 0.5 milligrammes per gramme. Propylene glycol, sorbitan sesquioleate, and white petrolatum are nonmedicinal substances.
0.05% Scalp Application;
Clobetasol 17-propionate is 0.5 milligrammes per gramme. Carbomer 934P, isopropyl alcohol, filtered water, and sodium hydroxide for pH adjustment are nonmedicinal components.
What should I do with this medication?
Ointment and dermovate cream: Apply the drug sparingly to the affected area and gently rub it in 2 or 3 times each day. The total dose applied in a week should not exceed 50 g. On lesions near the eye, use this drug with caution. Take precautions to keep it from getting into your eyes.
Lotion;
Apply the lotion to the affected areas of skin twice daily and rub it in thoroughly. In a week, the total dose should not exceed 50 g (50 mL).
Scalp lotion;
Apply the lotion to the affected areas of the scalp once or twice daily and gently rub it in. The total dose should not be more than 50 ml.
Spray the solution on the afflicted regions of skin twice daily and gently rub it in. The total dose should not exceed 50 mL per week and should not be used for more than 4 weeks.
Shampoo;
Apply a thin layer of clobetasol shampoo to the affected area of the scalp once daily. The shampoo is applied to the lesions on dry scalp and rubbed in gently. Allow it to sit for 15 minutes before soaking, lathering, and rinsing your hair. The total dose applied in a week should not exceed 50 mL.
Wash your hands well before and after applying clobetasol;
Many factors can influence a person’s medicine dose, including body weight and other medical conditions. If your doctor has prescribed a dose other than those listed below, do not alter your drug regimen without first checking with your doctor.
As a result, you should only use clobetasol 17 – propionate for short periods of time and discontinue it as soon as the condition resolves. This medication should not be used under dressings that don’t breathe.
If you haven’t seen any improvement in your skin after a week, discontinue use and consult your doctor.
It is critical that you take this medication exactly as directed by your doctor. If you miss a dose, apply it as soon as possible and continue with your regular regimen. If your next dose is approaching,
Keep this medication at room temperature, away from light, and out of the reach of children. The spray is flammable and should be stored away from heat or flame.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who is NOT supposed to take this medication dermovate cream ?
Clobetasol 17-propionate should not be used or administered to anyone who is:
is allergic to clobetasol propionate or any of the medication’s constituents is allergic to other corticosteroids
is less than a year old
Clobetasol 17 – propionate should not be used to treat: untreated bacterial, fungal, viral (herpes simplex, skin rash following immunisation, chickenpox), or tuberculous skin lesions.
vulgaris acne;
Itching around the anus and genitals, dermatitis around the mouth
Rosacea affected the skin around the eyes and around the eyelids.
What are the possible negative effects of this medication?
Many drugs can have negative side effects. A side effect is an undesired reaction to a medicine when taken at the recommended dose. Side effects might be mild or severe, and they can be transitory or permanent.
The following side effects are not experienced by everyone who takes this drug. If you are concerned about side effects, talk to your doctor about the risks and advantages of this drug.
At least 1% of patients taking this medicine have reported the following side effects. Many of these side effects are manageable, and some may go away on their own.
Contact your doctor if any of these side effects are severe or bothersome. Your chemist could may be able to advise you on how to deal with side effects.
. Skin burning, dryness, irritation, itching, or redness (generally moderate and transient)
. increased redness or scaling of skin sores (usually moderate and transient)
. Itching and skin colour changes
. Infection of the skin used to dermovate cream
. skin rash (usually minor and transient)
. the skin weakening and ripping
. Skin thinning with easy bruising
. tingling, prickling sensation of slow-healing skin wounds.
Although most of the adverse effects listed below are uncommon, they can be significant if you do not consult your doctor or seek medical assistance.
If any of the following side effects develop, consult your doctor as soon as possible:
. Acne-prone or oily skin used dermovate cream
. Skin allergy (red rash, dry scaly skin, swelling, soreness, crusting, leaking)
. general sense of ill-health lack of skin healing unpleasant, red, or itchy pus-containing blisters in hair follicles
. unusual hair growth, particularly on the face visible lines or small blood vessels under the skin
. Cataract symptoms (such as clouding of the lens of the eye, blurred vision, poor vision, and eye pain)
. glaucoma symptoms (e.g., hazy vision, seeing double).
The following side effects may occur if this medication is used improperly or for a long time;
Vision blurring or loss (occurs gradually if certain products are used near the eye)
filling or rounding out of the face
. increased blood pressure
. irregular heartbeat
. irregular menstrual periods
. irritability
. skin irritation around the mouth loss of appetite
. depression
. cramps, pain, or weakness in the muscles
. rapid weight gain or loss
. stomach bloating, burning, cramping, or pain
. swelling of feet or lower legs
. dermovate cream
. unusual bruising
. unusual decrease in sexual desire or ability (in men)
. unexpected weariness or weakness vomiting weakness of the arms, legs, or trunk (severe)
worsening of infections.
If any of the following occur, discontinue use of the drug and seek emergency medical attention;
Symptoms of a severe allergic reaction (such as difficulty breathing, dizziness, itching, rash, and swelling)
symptoms of high levels of corticosteroids in the blood stream (e.g., fatigue, increased thirst and urination, irritability, muscle weakness)
Nausea, vomiting, dizziness, fever, and chest pain are all indications of diminished adrenal function.
Other than the stated adverse effects, some persons may encounter them. Consult your doctor if you develop any symptoms that concern you while taking this medicine.
Are there any other risks or warnings for this medication?
Before you start taking a medicine, tell your doctor about any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other important health information. These factors may have an impact on how you use this medication.
Inform all of your doctors that you are utilising topical corticosteroids (skin-applied).
Absorption;
When clobetasol 17 – propionate is applied to large areas for extended periods of time and under non-breathable dressings, it is conceivable that enough drug will be absorbed into the bloodstream to induce undesired side effects. As a result, it is best to use this dermovate cream for short periods of time and then discontinue it.
Diabetes;
When clobetasol 17-propionate is applied to large parts of the body for extended periods of time or under dressings that do not breathe, enough medication may be absorbed into the bloodstream to impact blood sugar levels. If you have diabetes, your doctor should regularly monitor your condition while you use clobetasol 17-propionate because it can influence blood sugar control (either increasing or decreasing blood sugar levels).
Eyes;
Do not use this dermovate cream on lesions near the eyes or on the eyelids. Getting the drug in your eye can increase your chance of developing high blood pressure, glaucoma, cataracts, or infection. Contact your doctor as soon as you notice any eye symptoms, such as impaired vision or pain.
Infection;
Topical corticosteroids may increase the likelihood of a skin infection developing. If you observe any increased redness, swelling, heat, or pain around the region where the drug is given, contact your doctor right away because these are possible indicators of infection.
Corticosteroids can build up in the body as a result of decreased liver function or liver disease, causing negative effects. If you have liver problems, talk to your doctor about how this drug might influence your medical condition, how your medical condition might affect the administration and effectiveness of this medication, and whether you need any additional monitoring.
Long-term use;
Some persons report that the effectiveness of clobetasol diminishes after prolonged use. There have also been reports of psoriasis worsening or the formation of a new kind of psoriasis. This drug should only be used until the condition has resolved.
Inform all health professionals engaged in your care that you have been using a topical (skin-applied) corticosteroid.
Skin thinning;
Using topical corticosteroid drugs over an extended period of time might cause skin to thin, soften, and form stretch marks. Your doctor may advise you to take a break from using this medication or to only apply it to one area of your body at a time. Psoriasis may reappear if corticosteroid therapy is abruptly discontinued.
Pregnancy;
If the benefits outweigh the dangers, this medicine should not be used during pregnancy. If you become pregnant while using this medicine, notify your doctor right away.
Breast-feeding;
This drug may be excreted in breast milk. Clobetasol 17-propionate may have an effect on your infant if you are breastfeeding. Discuss with your doctor if you should continue breast-feeding.
Seniors;
People over the age of 65 may need to take less of this drug or take it less frequently.
What other medications might interact with this one?
Clobetasol 17 – propionate may have an interaction with any of the following;
aldesleukin and other corticosteroid-containing topical medicines
Topical itraconazole and ritonavir medicines that cause skin irritation.
Speak with your doctor or chemist if you are taking any of these medications. Depending on your unique situation, your doctor may advise you to:
Stop taking one of the prescriptions, switch to another, change the way you take one or both of the medications, or leave things alone.
An interaction between two drugs may not always necessitate the discontinuation of one of them. Discuss with your doctor how any drug interactions are or should be treated.
Other medications, in addition to those listed above, may interact with this medicine. Inform your doctor or prescriber about all prescription, non-prescription, and herbal medications you are using. Tell them about any supplements you use as well. Because coffee, alcohol, nicotine from cigarettes, or illicit drugs can interfere with the action of many medications, you should inform your doctor if you use them.
